Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility.
OBJECTIVE: To study whether common genetic variants of the genes involved in the complex regulatory mechanism determining the intracellular bio-availability of T3 influence osteoarthritis onset. METHODS: In total 17 genetic variants within the genes encoding WD40-repeat/SOCS-box protein 1, ubiquiti...
Main Authors: | Meulenbelt, I, Bos, S, Chapman, K, van der Breggen, R, Houwing-Duistermaat, J, Kremer, D, Kloppenburg, M, Carr, A, Tsezou, A, González, A, Loughlin, J, Slagboom, P |
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Format: | Journal article |
Language: | English |
Published: |
2011
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