Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility.

Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility.

OBJECTIVE: To study whether common genetic variants of the genes involved in the complex regulatory mechanism determining the intracellular bio-availability of T3 influence osteoarthritis onset. METHODS: In total 17 genetic variants within the genes encoding WD40-repeat/SOCS-box protein 1, ubiquiti...

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Bibliografiske detaljer
Main Authors:	Meulenbelt, I, Bos, S, Chapman, K, van der Breggen, R, Houwing-Duistermaat, J, Kremer, D, Kloppenburg, M, Carr, A, Tsezou, A, González, A, Loughlin, J, Slagboom, P
Format:	Journal article
Sprog:	English
Udgivet:	2011

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