A general approach for haplotype phasing across the full spectrum of relatedness

A general approach for haplotype phasing across the full spectrum of relatedness

Many existing cohorts contain a range of relatedness between genotyped individuals, either by design or by chance. Haplotype estimation in such cohorts is a central step in many downstream analyses. Using genotypes from six cohorts from isolated populations and two cohorts from non-isolated populati...

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Main Authors: O'Connell, J, Gurdasani, D, Delaneau, O, Pirastu, N, Ulivi, S, Cocca, M, Traglia, M, Huang, J, Huffman, J, Rudan, I, McQuillan, R, Fraser, R, Campbell, H, Polasek, O, Asiki, G, Ekoru, K, Hayward, C, Wright, A, Vitart, V, Navarro, P, Zagury, J, Wilson, J, Toniolo, D, Gasparini, P, Soranzo, N, Sandhu, MS, Marchini, J
Format: Journal article
Language:English
Published: Public Library of Science 2014

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