Copper-mediated radiosynthesis of 18F- and 123I-radiolabelled PARP inhibitors
<p>This thesis aims to develop copper-mediated radiosynthesis to incorporate fluorine-18 and iodine-123 into FDA-approved poly(ADP-ribose) polymerase (PARP) inhibitors for cancer diagnosis and treatment, consisting the development of 18F-radiolabelled rucaparib for positron emission tomograph...
Main Author: | Chen, Z |
---|---|
Other Authors: | Gouverneur, V |
Format: | Thesis |
Language: | English |
Published: |
2022
|
Similar Items
-
Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [18F]olaparib
by: Guibbal, F, et al.
Published: (2020) -
Copper-mediated radiosynthesis of [18F]rucaparib
by: Chen, Z, et al.
Published: (2021) -
Convergent F-18 radiosynthesis: A new dimension for radiolabelling
by: Li, L, et al.
Published: (2011) -
[18F]Olaparib: Precision radiolabelling of PARP inhibitors for in vivo imaging
by: Wilson, T, et al.
Published: (2018) -
Convergent 18F Radiosynthesis
by: Gouverneur, V, et al.
Published: (2012)