Copper-mediated radiosynthesis of 18F- and 123I-radiolabelled PARP inhibitors

<p>This thesis aims to develop copper-mediated radiosynthesis to incorporate fluorine-18 and iodine-123 into FDA-approved poly(ADP-ribose) polymerase (PARP) inhibitors for cancer diagnosis and treatment, consisting the development of 18F-radiolabelled rucaparib for positron emission tomograph...

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Bibliographic Details
Main Author: Chen, Z
Other Authors: Gouverneur, V
Format: Thesis
Language:English
Published: 2022

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