Copper-mediated radiosynthesis of 18F- and 123I-radiolabelled PARP inhibitors

<p>This thesis aims to develop copper-mediated radiosynthesis to incorporate fluorine-18 and iodine-123 into FDA-approved poly(ADP-ribose) polymerase (PARP) inhibitors for cancer diagnosis and treatment, consisting the development of 18F-radiolabelled rucaparib for positron emission tomograph...

Popoln opis

Bibliografske podrobnosti
Glavni avtor: Chen, Z
Drugi avtorji: Gouverneur, V
Format: Thesis
Jezik:English
Izdano: 2022