Copper-mediated radiosynthesis of 18F- and 123I-radiolabelled PARP inhibitors
<p>This thesis aims to develop copper-mediated radiosynthesis to incorporate fluorine-18 and iodine-123 into FDA-approved poly(ADP-ribose) polymerase (PARP) inhibitors for cancer diagnosis and treatment, consisting the development of 18F-radiolabelled rucaparib for positron emission tomograph...
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Format: | Thesis |
Jezik: | English |
Izdano: |
2022
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