Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study

<br><strong>Background </strong>Most of the deaths among neonates in low-income and middle-income countries (LMICs) can be prevented through universal access to basic high-quality health services including essential facility-based inpatient care. However, poor routine data undermin...

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Main Authors: Irimu, G, Aluvaala, J, Malla, L, Omoke, S, Ogero, M, Mbevi, G, Waiyego, M, Mwangi, C, Were, F, Gathara, D, Agweyu, A, Akech, S, English, M, Clinical Information Network authors
Format: Journal article
Language:English
Published: BMJ Publishing Group 2021
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author Irimu, G
Aluvaala, J
Malla, L
Omoke, S
Ogero, M
Mbevi, G
Waiyego, M
Mwangi, C
Were, F
Gathara, D
Agweyu, A
Akech, S
English, M
Clinical Information Network authors
author_facet Irimu, G
Aluvaala, J
Malla, L
Omoke, S
Ogero, M
Mbevi, G
Waiyego, M
Mwangi, C
Were, F
Gathara, D
Agweyu, A
Akech, S
English, M
Clinical Information Network authors
author_sort Irimu, G
collection OXFORD
description <br><strong>Background </strong>Most of the deaths among neonates in low-income and middle-income countries (LMICs) can be prevented through universal access to basic high-quality health services including essential facility-based inpatient care. However, poor routine data undermines data-informed efforts to monitor and promote improvements in the quality of newborn care across hospitals. <br><strong> Methods </strong>Continuously collected routine patients’ data from structured paper record forms for all admissions to newborn units (NBUs) from 16 purposively selected Kenyan public hospitals that are part of a clinical information network were analysed together with data from all paediatric admissions ages 0–13 years from 14 of these hospitals. Data are used to show the proportion of all admissions and deaths in the neonatal age group and examine morbidity and mortality patterns, stratified by birth weight, and their variation across hospitals. <br><strong> Findings </strong>During the 354 hospital months study period, 90 222 patients were admitted to the 14 hospitals contributing NBU and general paediatric ward data. 46% of all the admissions were neonates (aged 0–28 days), but they accounted for 66% of the deaths in the age group 0–13 years. 41 657 inborn neonates were admitted in the NBUs across the 16 hospitals during the study period. 4266/41 657 died giving a crude mortality rate of 10.2% (95% CI 9.97% to 10.55%), with 60% of these deaths occurring on the first-day of admission. Intrapartum-related complications was the single most common diagnosis among the neonates with birth weight of 2000 g or more who died. A threefold variation in mortality across hospitals was observed for birth weight categories 1000–1499 g and 1500–1999 g. <br><strong> Interpretation </strong>The high proportion of neonatal deaths in hospitals may reflect changing patterns of childhood mortality. Majority of newborns died of preventable causes (>95%). Despite availability of high-impact low-cost interventions, hospitals have high and very variable mortality proportions after stratification by birth weight.
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spelling oxford-uuid:854d73ce-4ac9-49a3-877a-f4a8ea76c7512022-03-26T21:56:43ZNeonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort studyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:854d73ce-4ac9-49a3-877a-f4a8ea76c751EnglishSymplectic ElementsBMJ Publishing Group2021Irimu, GAluvaala, JMalla, LOmoke, SOgero, MMbevi, GWaiyego, MMwangi, CWere, FGathara, DAgweyu, AAkech, SEnglish, MClinical Information Network authors<br><strong>Background </strong>Most of the deaths among neonates in low-income and middle-income countries (LMICs) can be prevented through universal access to basic high-quality health services including essential facility-based inpatient care. However, poor routine data undermines data-informed efforts to monitor and promote improvements in the quality of newborn care across hospitals. <br><strong> Methods </strong>Continuously collected routine patients’ data from structured paper record forms for all admissions to newborn units (NBUs) from 16 purposively selected Kenyan public hospitals that are part of a clinical information network were analysed together with data from all paediatric admissions ages 0–13 years from 14 of these hospitals. Data are used to show the proportion of all admissions and deaths in the neonatal age group and examine morbidity and mortality patterns, stratified by birth weight, and their variation across hospitals. <br><strong> Findings </strong>During the 354 hospital months study period, 90 222 patients were admitted to the 14 hospitals contributing NBU and general paediatric ward data. 46% of all the admissions were neonates (aged 0–28 days), but they accounted for 66% of the deaths in the age group 0–13 years. 41 657 inborn neonates were admitted in the NBUs across the 16 hospitals during the study period. 4266/41 657 died giving a crude mortality rate of 10.2% (95% CI 9.97% to 10.55%), with 60% of these deaths occurring on the first-day of admission. Intrapartum-related complications was the single most common diagnosis among the neonates with birth weight of 2000 g or more who died. A threefold variation in mortality across hospitals was observed for birth weight categories 1000–1499 g and 1500–1999 g. <br><strong> Interpretation </strong>The high proportion of neonatal deaths in hospitals may reflect changing patterns of childhood mortality. Majority of newborns died of preventable causes (>95%). Despite availability of high-impact low-cost interventions, hospitals have high and very variable mortality proportions after stratification by birth weight.
spellingShingle Irimu, G
Aluvaala, J
Malla, L
Omoke, S
Ogero, M
Mbevi, G
Waiyego, M
Mwangi, C
Were, F
Gathara, D
Agweyu, A
Akech, S
English, M
Clinical Information Network authors
Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study
title Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study
title_full Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study
title_fullStr Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study
title_full_unstemmed Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study
title_short Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study
title_sort neonatal mortality in kenyan hospitals a multisite retrospective cohort study
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