$Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL.$

Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL.

Although TP53, NOTCH1, and SF3B1 mutations may impair prognosis of patients with chronic lymphocytic leukemia (CLL) receiving frontline therapy, the impact of these mutations or any other, alone or in combination, remains unclear at relapse. The genome of 114 relapsed/refractory patients included in...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Guièze, R, Robbe, P, Clifford, R, de Guibert, S, Pereira, B, Timbs, A, Dilhuydy, M, Cabes, M, Ysebaert, L, Burns, A, Nguyen-Khac, F, Davi, F, Véronèse, L, Combes, P, Le Garff-Tavernier, M, Leblond, V, Merle-Béral, H, Alsolami, R, Hamblin, A, Mason, J, Pettitt, A, Hillmen, P, Taylor, J, Knight, S, Tournilhac, O, Schuh, A
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	American Society of Hematology 2015

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