Transcutaneous monitoring of blood gases: is it comparable with arterialized earlobe sampling?

Researchers are increasingly looking for reliable non-invasive methods of assessing blood gas concentrations, and several new techniques have recently become available. Values derived using arterialized earlobe samples have been found to be comparable with conventional arterial samples, and recent s...

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Main Authors: Dawson, S, Cave, C, Pavord, I, Potter, J
Format: Journal article
Language:English
Published: 1998
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author Dawson, S
Cave, C
Pavord, I
Potter, J
author_facet Dawson, S
Cave, C
Pavord, I
Potter, J
author_sort Dawson, S
collection OXFORD
description Researchers are increasingly looking for reliable non-invasive methods of assessing blood gas concentrations, and several new techniques have recently become available. Values derived using arterialized earlobe samples have been found to be comparable with conventional arterial samples, and recent studies have compared transcutaneous blood gas analysis with the traditional arterial samples and found a reasonable level of agreement in particular for the partial pressure of carbon dioxide. There are no data comparing oxygen and carbon dioxide partial pressures (pO2, pCO2) derived from arterialized samples with one of the newer transcutaneous techniques. We therefore simultaneously studied arterialized earlobe blood gas samples and values for pO2 and pCO2 obtained by a transcutaneous monitor (TINA, Radiometer, Copenhagen) in 26 subjects with varying blood gas values. There was a close agreement between the two methods for assessment of pCO2 [mean difference (95% C.I.) between transcutaneous and earlobe values 0.25 kPa (-0.004, 0.5 kPa)], but not for pO2 [1.71 kPa (0.35, 3.07 kPa)]. Similarly, the limits of agreement were narrow for pCO2 compared to those for pO2 (-0.98, 1.47 kPa and -6.44, 3.02 kPa respectively). We conclude that transcutaneous measurement of pCO2 using the TINA is acceptable in the research setting, whereas assessment of pO2 cannot reliably be made using this technique.
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spelling oxford-uuid:85a5e55c-732d-4f03-bbf9-eb75cd7a5b902022-03-26T21:58:55ZTranscutaneous monitoring of blood gases: is it comparable with arterialized earlobe sampling?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:85a5e55c-732d-4f03-bbf9-eb75cd7a5b90EnglishSymplectic Elements at Oxford1998Dawson, SCave, CPavord, IPotter, JResearchers are increasingly looking for reliable non-invasive methods of assessing blood gas concentrations, and several new techniques have recently become available. Values derived using arterialized earlobe samples have been found to be comparable with conventional arterial samples, and recent studies have compared transcutaneous blood gas analysis with the traditional arterial samples and found a reasonable level of agreement in particular for the partial pressure of carbon dioxide. There are no data comparing oxygen and carbon dioxide partial pressures (pO2, pCO2) derived from arterialized samples with one of the newer transcutaneous techniques. We therefore simultaneously studied arterialized earlobe blood gas samples and values for pO2 and pCO2 obtained by a transcutaneous monitor (TINA, Radiometer, Copenhagen) in 26 subjects with varying blood gas values. There was a close agreement between the two methods for assessment of pCO2 [mean difference (95% C.I.) between transcutaneous and earlobe values 0.25 kPa (-0.004, 0.5 kPa)], but not for pO2 [1.71 kPa (0.35, 3.07 kPa)]. Similarly, the limits of agreement were narrow for pCO2 compared to those for pO2 (-0.98, 1.47 kPa and -6.44, 3.02 kPa respectively). We conclude that transcutaneous measurement of pCO2 using the TINA is acceptable in the research setting, whereas assessment of pO2 cannot reliably be made using this technique.
spellingShingle Dawson, S
Cave, C
Pavord, I
Potter, J
Transcutaneous monitoring of blood gases: is it comparable with arterialized earlobe sampling?
title Transcutaneous monitoring of blood gases: is it comparable with arterialized earlobe sampling?
title_full Transcutaneous monitoring of blood gases: is it comparable with arterialized earlobe sampling?
title_fullStr Transcutaneous monitoring of blood gases: is it comparable with arterialized earlobe sampling?
title_full_unstemmed Transcutaneous monitoring of blood gases: is it comparable with arterialized earlobe sampling?
title_short Transcutaneous monitoring of blood gases: is it comparable with arterialized earlobe sampling?
title_sort transcutaneous monitoring of blood gases is it comparable with arterialized earlobe sampling
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AT cavec transcutaneousmonitoringofbloodgasesisitcomparablewitharterializedearlobesampling
AT pavordi transcutaneousmonitoringofbloodgasesisitcomparablewitharterializedearlobesampling
AT potterj transcutaneousmonitoringofbloodgasesisitcomparablewitharterializedearlobesampling