Epigenetic protein families: a new frontier for drug discovery.

Epigenetic regulation of gene expression is a dynamic and reversible process that establishes normal cellular phenotypes but also contributes to human diseases. At the molecular level, epigenetic regulation involves hierarchical covalent modification of DNA and the proteins that package DNA, such as...

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Autors principals: Arrowsmith, C, Bountra, C, Fish, P, Lee, K, Schapira, M
Format: Journal article
Idioma:English
Publicat: 2012