Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.

To clarify the position of the TNFA and TNFB genes on the HLA map, we have assigned TNFA to large DNA restriction fragments separated by field inversion gel electrophoresis, which hybridize with either class III- or class I-specific probes as well. These results prove that the TNFA locus is localize...

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Main Authors: Ragoussis, J, Bloemer, K, Weiss, E, Ziegler, A
Format: Journal article
Language:English
Published: 1988
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author Ragoussis, J
Bloemer, K
Weiss, E
Ziegler, A
author_facet Ragoussis, J
Bloemer, K
Weiss, E
Ziegler, A
author_sort Ragoussis, J
collection OXFORD
description To clarify the position of the TNFA and TNFB genes on the HLA map, we have assigned TNFA to large DNA restriction fragments separated by field inversion gel electrophoresis, which hybridize with either class III- or class I-specific probes as well. These results prove that the TNFA locus is localized between the HLA class III region and the HLA-B locus.
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spelling oxford-uuid:85bb0a36-9ace-4552-872f-159a2e82ae0a2022-03-26T21:59:24ZLocalization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:85bb0a36-9ace-4552-872f-159a2e82ae0aEnglishSymplectic Elements at Oxford1988Ragoussis, JBloemer, KWeiss, EZiegler, ATo clarify the position of the TNFA and TNFB genes on the HLA map, we have assigned TNFA to large DNA restriction fragments separated by field inversion gel electrophoresis, which hybridize with either class III- or class I-specific probes as well. These results prove that the TNFA locus is localized between the HLA class III region and the HLA-B locus.
spellingShingle Ragoussis, J
Bloemer, K
Weiss, E
Ziegler, A
Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.
title Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.
title_full Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.
title_fullStr Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.
title_full_unstemmed Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.
title_short Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis.
title_sort localization of the genes for tumor necrosis factor and lymphotoxin between the hla class i and iii regions by field inversion gel electrophoresis
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