| Summary: | <p><strong>Objective:</strong> To ensure clinicians can rely on point-of-care testing results, we assessed agreement between point-of-care tests for creatinine, urea, sodium, potassium, calcium, Hb, INR, CRP and subsequent corresponding laboratory tests.</p>
<p><strong>Participants:</strong> Community-dwelling adults referred to a community-based acute ambulatory care unit.</p>
<p><strong>Interventions:</strong> The Abbott i-STATTM (Hb, clinical chemistry, INR) and the AfinionTM Analyser (CRP) and corresponding laboratory analyses.</p>
<p><strong>Outcomes:</strong> Agreement (Bland-Altman) and bias (Passing-Bablok regression).</p>
<p><strong>Results:</strong> Among 462 adults we found an absolute mean difference between point-of-care and central laboratory analyses of 6.4g/L (95%LOA -7.9 to +20.6) for haemoglobin, -0.5mmol/L (95%LOA -4.5 to +3.5) for sodium, 0.2mmol/L (95%LOA -0.6 to +0.9) for potassium, 0.0mmol/L (95%LOA -0.3 to +0.3) for calcium, 9.0 μmol/L (95%LOA -18.5 to +36.4) for creatinine, 0.0mmol/L (95%LOA -2.7 to +2.6) for urea, -0.2 (95%LOA -2.4 to +2.0) for INR, -5.0 mg/L (95%LOA -24.4 to +14.4) for CRP.</p>
<p><strong>Conclusions:</strong> There was acceptable agreement and bias for these analytes, except for haemoglobin and creatinine.</p>
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