Clinical reliability of point-of-care tests to support community based acute ambulatory care
<p><strong>Objective:</strong> To ensure clinicians can rely on point-of-care testing results, we assessed agreement between point-of-care tests for creatinine, urea, sodium, potassium, calcium, Hb, INR, CRP and subsequent corresponding laboratory tests.</p> <p><str...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Rila Publications Ltd
2020
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| _version_ | 1797079664460562432 |
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| author | Verbakel, JY Richardson, C Elias, T Bowen, J Hassanzadeh, R Shine, B Smith, I Hayward, G Van den Bruel, A Pendlebury, ST Lasserson, D |
| author_facet | Verbakel, JY Richardson, C Elias, T Bowen, J Hassanzadeh, R Shine, B Smith, I Hayward, G Van den Bruel, A Pendlebury, ST Lasserson, D |
| author_sort | Verbakel, JY |
| collection | OXFORD |
| description | <p><strong>Objective:</strong> To ensure clinicians can rely on point-of-care testing results, we assessed agreement between point-of-care tests for creatinine, urea, sodium, potassium, calcium, Hb, INR, CRP and subsequent corresponding laboratory tests.</p>
<p><strong>Participants:</strong> Community-dwelling adults referred to a community-based acute ambulatory care unit.</p>
<p><strong>Interventions:</strong> The Abbott i-STATTM (Hb, clinical chemistry, INR) and the AfinionTM Analyser (CRP) and corresponding laboratory analyses.</p>
<p><strong>Outcomes:</strong> Agreement (Bland-Altman) and bias (Passing-Bablok regression).</p>
<p><strong>Results:</strong> Among 462 adults we found an absolute mean difference between point-of-care and central laboratory analyses of 6.4g/L (95%LOA -7.9 to +20.6) for haemoglobin, -0.5mmol/L (95%LOA -4.5 to +3.5) for sodium, 0.2mmol/L (95%LOA -0.6 to +0.9) for potassium, 0.0mmol/L (95%LOA -0.3 to +0.3) for calcium, 9.0 μmol/L (95%LOA -18.5 to +36.4) for creatinine, 0.0mmol/L (95%LOA -2.7 to +2.6) for urea, -0.2 (95%LOA -2.4 to +2.0) for INR, -5.0 mg/L (95%LOA -24.4 to +14.4) for CRP.</p>
<p><strong>Conclusions:</strong> There was acceptable agreement and bias for these analytes, except for haemoglobin and creatinine.</p> |
| first_indexed | 2024-03-07T00:49:06Z |
| format | Journal article |
| id | oxford-uuid:85bfe316-fcce-4907-86dc-684385f0caa5 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:49:06Z |
| publishDate | 2020 |
| publisher | Rila Publications Ltd |
| record_format | dspace |
| spelling | oxford-uuid:85bfe316-fcce-4907-86dc-684385f0caa52022-03-26T21:59:39ZClinical reliability of point-of-care tests to support community based acute ambulatory careJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:85bfe316-fcce-4907-86dc-684385f0caa5EnglishSymplectic Elements at OxfordRila Publications Ltd2020Verbakel, JYRichardson, CElias, TBowen, JHassanzadeh, RShine, BSmith, IHayward, GVan den Bruel, APendlebury, STLasserson, D<p><strong>Objective:</strong> To ensure clinicians can rely on point-of-care testing results, we assessed agreement between point-of-care tests for creatinine, urea, sodium, potassium, calcium, Hb, INR, CRP and subsequent corresponding laboratory tests.</p> <p><strong>Participants:</strong> Community-dwelling adults referred to a community-based acute ambulatory care unit.</p> <p><strong>Interventions:</strong> The Abbott i-STATTM (Hb, clinical chemistry, INR) and the AfinionTM Analyser (CRP) and corresponding laboratory analyses.</p> <p><strong>Outcomes:</strong> Agreement (Bland-Altman) and bias (Passing-Bablok regression).</p> <p><strong>Results:</strong> Among 462 adults we found an absolute mean difference between point-of-care and central laboratory analyses of 6.4g/L (95%LOA -7.9 to +20.6) for haemoglobin, -0.5mmol/L (95%LOA -4.5 to +3.5) for sodium, 0.2mmol/L (95%LOA -0.6 to +0.9) for potassium, 0.0mmol/L (95%LOA -0.3 to +0.3) for calcium, 9.0 μmol/L (95%LOA -18.5 to +36.4) for creatinine, 0.0mmol/L (95%LOA -2.7 to +2.6) for urea, -0.2 (95%LOA -2.4 to +2.0) for INR, -5.0 mg/L (95%LOA -24.4 to +14.4) for CRP.</p> <p><strong>Conclusions:</strong> There was acceptable agreement and bias for these analytes, except for haemoglobin and creatinine.</p> |
| spellingShingle | Verbakel, JY Richardson, C Elias, T Bowen, J Hassanzadeh, R Shine, B Smith, I Hayward, G Van den Bruel, A Pendlebury, ST Lasserson, D Clinical reliability of point-of-care tests to support community based acute ambulatory care |
| title | Clinical reliability of point-of-care tests to support community based acute ambulatory care |
| title_full | Clinical reliability of point-of-care tests to support community based acute ambulatory care |
| title_fullStr | Clinical reliability of point-of-care tests to support community based acute ambulatory care |
| title_full_unstemmed | Clinical reliability of point-of-care tests to support community based acute ambulatory care |
| title_short | Clinical reliability of point-of-care tests to support community based acute ambulatory care |
| title_sort | clinical reliability of point of care tests to support community based acute ambulatory care |
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