Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism
Immunotherapy based on checkpoint inhibitors is providing substantial clinical benefit, but only to a minority of cancer patients. The current priority is to understand why the majority of patients fail to respond. Besides T-cell dysfunction, T-cell apoptosis was reported in several recent studies a...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer Berlin Heidelberg
2018
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