Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition.

Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition.

p300 is a transcriptional cofactor and prototype histone acetyltransferase involved in regulating multiple cellular processes. We generated p300 deficient (p300-) cells from the colon carcinoma cell line HCT116 by gene targeting. Comparison of epithelial and mesenchymal proteins in p300- with parent...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Krubasik, D, Iyer, N, English, W, Ahmed, A, Vias, M, Roskelley, C, Brenton, J, Caldas, C, Murphy, G
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2006

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