Palladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindoles
A series of 3-(2-haloalkenyl)-2-pyridyl-halides undergo consecutive palladium-catalysed inter- and intramolecular amination reactions to deliver a series of 1-functionalised 7-azaindoles. Anilines and amines can be readily employed as the N-nucleophile and incorporation of both electron-donating and...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2009
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| _version_ | 1797079693094027264 |
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| author | Hodgkinson, R Schulz, J Willis, M |
| author_facet | Hodgkinson, R Schulz, J Willis, M |
| author_sort | Hodgkinson, R |
| collection | OXFORD |
| description | A series of 3-(2-haloalkenyl)-2-pyridyl-halides undergo consecutive palladium-catalysed inter- and intramolecular amination reactions to deliver a series of 1-functionalised 7-azaindoles. Anilines and amines can be readily employed as the N-nucleophile and incorporation of both electron-donating and electron withdrawing substituents on the pyridine core is possible. © 2009 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-07T00:49:24Z |
| format | Journal article |
| id | oxford-uuid:85da0a2f-e23c-4102-bd69-e042ee65bc83 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:49:24Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:85da0a2f-e23c-4102-bd69-e042ee65bc832022-03-26T22:00:09ZPalladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindolesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:85da0a2f-e23c-4102-bd69-e042ee65bc83EnglishSymplectic Elements at Oxford2009Hodgkinson, RSchulz, JWillis, MA series of 3-(2-haloalkenyl)-2-pyridyl-halides undergo consecutive palladium-catalysed inter- and intramolecular amination reactions to deliver a series of 1-functionalised 7-azaindoles. Anilines and amines can be readily employed as the N-nucleophile and incorporation of both electron-donating and electron withdrawing substituents on the pyridine core is possible. © 2009 Elsevier Ltd. All rights reserved. |
| spellingShingle | Hodgkinson, R Schulz, J Willis, M Palladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindoles |
| title | Palladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindoles |
| title_full | Palladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindoles |
| title_fullStr | Palladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindoles |
| title_full_unstemmed | Palladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindoles |
| title_short | Palladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindoles |
| title_sort | palladium catalysed tandem alkenyl and aryl c n bond formation a cascade n annulation route to 1 functionalised 7 azaindoles |
| work_keys_str_mv | AT hodgkinsonr palladiumcatalysedtandemalkenylandarylcnbondformationacascadenannulationrouteto1functionalised7azaindoles AT schulzj palladiumcatalysedtandemalkenylandarylcnbondformationacascadenannulationrouteto1functionalised7azaindoles AT willism palladiumcatalysedtandemalkenylandarylcnbondformationacascadenannulationrouteto1functionalised7azaindoles |