Distinct roles for the hypoxia-inducible transcription factors HIF-1alpha and HIF-2alpha in human osteoclast formation and function
Bone homeostasis is maintained by a balance between osteoblast-mediated bone formation and osteoclast-driven bone resorption. Hypoxia modulates this relationship partially via direct and indirect effects of the hypoxia-inducible factor-1 alpha (HIF-1α) transcription factor on osteoclast formation an...
मुख्य लेखक: | Knowles, H |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
Nature Research
2020
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समान संसाधन
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Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.
द्वारा: Sowter, H, और अन्य
प्रकाशित: (2003) -
Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.
द्वारा: Mole, D, और अन्य
प्रकाशित: (2009) -
Hypoxia, hypoxia-inducible factor (HIF) and bone homeostasis: focus on osteoclast-mediated bone resorption
द्वारा: Knowles, H
प्रकाशित: (2015) -
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.
द्वारा: Talks, K, और अन्य
प्रकाशित: (2000) -
HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia.
द्वारा: Freya M Mowat, और अन्य
प्रकाशित: (2010-06-01)