Improved quantification of HIV-1-infected CD4+ T cells using an optimised method of intracellular HIV-1 gag p24 antigen detection
The capacity of CD8+ T cells to inhibit HIV-1 replication in vitro strongly correlates with virus control in vivo. Post-hoc evaluations of HIV-1 vaccine candidates suggest that this immunological parameter is a promising benchmark of vaccine efficacy. Large-scale analysis of CD8+ T cell antiviral ac...
Main Authors: | Yang, H, Yorke, E, Hancock, G, Clutton, G, Sande, N, Angus, B, Smyth, R, Mak, J, Dorrell, L |
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Format: | Journal article |
Language: | English |
Published: |
2013
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