Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people.

A recent genome-wide association (GWA) study of late-onset Alzheimer's disease (LOAD) identified 15 novel single nucleotide polymorphisms (SNPs) independent of ApoE. We hypothesised that variants associated with LOAD are also associated with poor cognitive function in elderly populations. We me...

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Detalles Bibliográficos
Main Authors: Cluett, C, Brayne, C, Clarke, R, Evans, G, Matthews, F, Rubinsztein, D, Huppert, F, Llewellyn, D, Rice, N, Henley, W, Frayling, T, Murray, A, Melzer, D
Formato: Journal article
Idioma:English
Publicado: 2010