Striatal dopamine transporter function is facilitated by converging biology of α-synuclein and cholesterol

Striatal dopamine transporter function is facilitated by converging biology of α-synuclein and cholesterol

Striatal dopamine transporters (DAT) powerfully regulate dopamine signalling, and can contribute risk to degeneration in Parkinson’s disease (PD). DATs can interact with the neuronal protein α-synuclein, which is associated with the aetiology and molecular pathology of idiopathic and familial PD. He...

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Bibliographic Details
Main Authors:	Threlfell, S, Saeid Mohammadi, A, Ryan, B, Connor-Robson, N, Platt, N, Anand, R, Serres, F, Sharp, T, Bengoa-Vergniory, N, Wade-Martins, R, Ewing, A, Cragg, S, Brimblecombe, K
Format:	Journal article
Language:	English
Published:	Frontiers Media 2021

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