Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

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We present an approximate conditional and joint association analysis that can use summary-level statistics from a meta-analysis of genome-wide association studies (GWAS) and estimated linkage disequilibrium (LD) from a reference sample with individual-level genotype data. Using this method, we analy...

Podrobná bibliografie
Hlavní autoři:	Yang, J, Ferreira, T, Morris, A, Medland, SE, Madden, P, Heath, A, Martin, N, Montgomery, G, Weedon, M, Loos, R, Frayling, T, McCarthy, M, Hirschhorn, J, Goddard, M, Visscher, P
Médium:	Journal article
Vydáno:	2012

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