How RNA polymerase II terminates transcription in higher eukaryotes.

How RNA polymerase II terminates transcription in higher eukaryotes.

The termination of transcription of eukaryotic genes by RNA polymerase II, at first sight, appears to be a rather random process, with the heterogeneous transcripts produced being processed to generate their correct 3' ends. However, recent studies have revealed that specific termination or pau...

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Bibliografiske detaljer
Hovedforfatter:	Proudfoot, N
Format:	Journal article
Sprog:	English
Udgivet:	1989

Lignende værker

Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast.
af: Mischo, H, et al.
Udgivet: (2013)

Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut.
af: Proudfoot, N
Udgivet: (2016)

Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II.
af: Dye, M, et al.
Udgivet: (2001)

Molecular dissection of mammalian RNA polymerase II transcriptional termination.
af: West, S, et al.
Udgivet: (2008)

Transcriptional termination signals for RNA polymerase II in fission yeast.
af: Birse, C, et al.
Udgivet: (1997)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
af: Gromak, N, et al.
Udgivet: (2006)

A pause site for RNA polymerase II is associated with termination of transcription.
af: Enriquez-Harris, P, et al.
Udgivet: (1991)

A role for chromatin remodeling in transcriptional termination by RNA polymerase II.
af: Alén, C, et al.
Udgivet: (2002)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.
af: West, S, et al.
Udgivet: (2008)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination
af: West, S, et al.
Udgivet: (2008)

Transcription termination by RNA Polymerase II
af: White, E
Udgivet: (2012)

Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription
af: Qian Zhang, et al.
Udgivet: (2024-09-01)

Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination.
af: Kawauchi, J, et al.
Udgivet: (2008)

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II.
af: Dye, M, et al.
Udgivet: (1999)

Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species
af: Natalia Petrenko, et al.
Udgivet: (2021-09-01)

Exon tethering in transcription by RNA polymerase II.
af: Dye, M, et al.
Udgivet: (2006)

EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.
af: Osheim, Y, et al.
Udgivet: (1999)

AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination.
af: White, E, et al.
Udgivet: (2013)

Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.
af: Morillon, A, et al.
Udgivet: (2003)

Uncovering the mechanisms of transcription elongation by eukaryotic RNA polymerases I, II, and III
af: Ruth Q. Jacobs, et al.
Udgivet: (2022-11-01)

Optical tweezers studies of transcription by eukaryotic RNA polymerases
af: Lisica Ana, et al.
Udgivet: (2017-02-01)

Turnover and function of noncoding RNA polymerase II transcripts.
af: Dye, M, et al.
Udgivet: (2006)

Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I.
af: Braglia, P, et al.
Udgivet: (2010)

Transcription termination and RNA degradation contribute to silencing of RNA polymerase II transcription within heterochromatin.
af: Vasiljeva, L, et al.
Udgivet: (2008)

Co-transcriptional RNA cleavage provides a failsafe termination mechanism for yeast RNA polymerase I.
af: Braglia, P, et al.
Udgivet: (2011)

An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae.
af: Kobor, MS, et al.
Udgivet: (1999)

Definition of RNA polymerase II CoTC terminator elements in the human genome.
af: Nojima, T, et al.
Udgivet: (2013)

Role of R-loops in pause-dependent transcriptional termination of RNA polymerase II
af: Skourti-Stathaki, K
Udgivet: (2012)

Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p.
af: Prescott, E, et al.
Udgivet: (2004)

Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast.
af: Morillon, A, et al.
Udgivet: (2003)

Definition of RNA Polymerase II CoTC Terminator Elements in the Human Genome
af: Takayuki Nojima, et al.
Udgivet: (2013-04-01)

Cleavage/polyadenylation factor IA associates with the carboxyl-terminal domain of RNA polymerase II in Saccharomyces cerevisiae.
af: Barillà, D, et al.
Udgivet: (2001)

Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
af: Joshua E Mayfield, et al.
Udgivet: (2019-08-01)

RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination.
af: Jose F Victorino, et al.
Udgivet: (2020-03-01)

The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
af: Wittmann, S, et al.
Udgivet: (2017)

Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.
af: Eggermont, J, et al.
Udgivet: (1993)

A New Insight into MYC Action: Control of RNA Polymerase II Methylation and Transcription Termination
af: Fiorella Scagnoli, et al.
Udgivet: (2023-01-01)

Investigating the role of Dis2 phosphatase in RNA Polymerase II transcription termination in fission yeast
af: Kecman, T
Udgivet: (2018)

Engineering efficient termination of bacteriophage T7 RNA polymerase transcription
af: Diana G Calvopina-Chavez, et al.
Udgivet: (2022-03-01)

CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation
af: Tellier, M, et al.
Udgivet: (2022)