Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat.
Using [3H]diazepam binding, high concentrations of receptors were found in the frontal cortex and lateral amygdala. Infusions of chlordiazepoxide into the lateral amygdala induced a release of responding measured during the component of a conditioned emotional response task previously associated wit...
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Format: | Journal article |
Jezik: | English |
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1985
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author | Thomas, SR Lewis, M Iversen, S |
author_facet | Thomas, SR Lewis, M Iversen, S |
author_sort | Thomas, SR |
collection | OXFORD |
description | Using [3H]diazepam binding, high concentrations of receptors were found in the frontal cortex and lateral amygdala. Infusions of chlordiazepoxide into the lateral amygdala induced a release of responding measured during the component of a conditioned emotional response task previously associated with an aversive stimulus. The lateral amygdala appears to be an important component of the forebrain circuitry involved in the expression of anxiety and sensitive to benzodiazepine drugs. |
first_indexed | 2024-03-07T00:51:01Z |
format | Journal article |
id | oxford-uuid:866ae3db-410f-4774-b56f-c7d3c8baa51b |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T00:51:01Z |
publishDate | 1985 |
record_format | dspace |
spelling | oxford-uuid:866ae3db-410f-4774-b56f-c7d3c8baa51b2022-03-26T22:03:45ZCorrelation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:866ae3db-410f-4774-b56f-c7d3c8baa51bEnglishSymplectic Elements at Oxford1985Thomas, SRLewis, MIversen, SUsing [3H]diazepam binding, high concentrations of receptors were found in the frontal cortex and lateral amygdala. Infusions of chlordiazepoxide into the lateral amygdala induced a release of responding measured during the component of a conditioned emotional response task previously associated with an aversive stimulus. The lateral amygdala appears to be an important component of the forebrain circuitry involved in the expression of anxiety and sensitive to benzodiazepine drugs. |
spellingShingle | Thomas, SR Lewis, M Iversen, S Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat. |
title | Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat. |
title_full | Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat. |
title_fullStr | Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat. |
title_full_unstemmed | Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat. |
title_short | Correlation of [3H]diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat. |
title_sort | correlation of 3h diazepam binding density with anxiolytic locus in the amygdaloid complex of the rat |
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