Repertoire analysis of γδ T cells in the chicken enables functional annotation of the genomic region revealing highly variable pan-tissue TCR gamma V gene usage as well as identifying public and private repertoires
Background Despite increasing interest in γδ T cells and their non-classical behaviour, most studies focus on animals with low numbers of circulating γδ T cells, such as mice and humans. Arguably, γδ T cell functions might be more prominent in chickens where these cells form a higher proportion of t...
Main Authors: | Dixon, R, Preston, SG, Dascalu, S, Flammer, PG, Fiddaman, SR, McLoughlin, K, Boyd, A, Volf, J, Rychlik, I, Bonsall, MB, Kaspers, B, Smith, A |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2021
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