In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.

Reliable measures of antifungal drug susceptibility are needed. We tested the susceptibility of Cryptococcus neoformans from patients treated with amphotericin B. In vitro susceptibility employed a modified broth macrodilution method. We demonstrate a strong correlation between the quantitative meas...

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Main Authors: Larsen, R, Bauer, M, Brouwer, A, Sanchez, A, Thomas, A, Rajanuwong, A, Chierakul, W, Peacock, S, Day, N, White, N, Rinaldi, MG, Harrison, T
Format: Journal article
Language:English
Published: 2007
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author Larsen, R
Bauer, M
Brouwer, A
Sanchez, A
Thomas, A
Rajanuwong, A
Chierakul, W
Peacock, S
Day, N
White, N
Rinaldi, MG
Harrison, T
author_facet Larsen, R
Bauer, M
Brouwer, A
Sanchez, A
Thomas, A
Rajanuwong, A
Chierakul, W
Peacock, S
Day, N
White, N
Rinaldi, MG
Harrison, T
author_sort Larsen, R
collection OXFORD
description Reliable measures of antifungal drug susceptibility are needed. We tested the susceptibility of Cryptococcus neoformans from patients treated with amphotericin B. In vitro susceptibility employed a modified broth macrodilution method. We demonstrate a strong correlation between the quantitative measures of in vitro amphotericin B susceptibility and the quantitative response observed in patients.
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spelling oxford-uuid:868be6d9-0d9f-407b-bfa5-713cf9570dee2022-03-26T22:04:46ZIn vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:868be6d9-0d9f-407b-bfa5-713cf9570deeEnglishSymplectic Elements at Oxford2007Larsen, RBauer, MBrouwer, ASanchez, AThomas, ARajanuwong, AChierakul, WPeacock, SDay, NWhite, NRinaldi, MGHarrison, TReliable measures of antifungal drug susceptibility are needed. We tested the susceptibility of Cryptococcus neoformans from patients treated with amphotericin B. In vitro susceptibility employed a modified broth macrodilution method. We demonstrate a strong correlation between the quantitative measures of in vitro amphotericin B susceptibility and the quantitative response observed in patients.
spellingShingle Larsen, R
Bauer, M
Brouwer, A
Sanchez, A
Thomas, A
Rajanuwong, A
Chierakul, W
Peacock, S
Day, N
White, N
Rinaldi, MG
Harrison, T
In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.
title In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.
title_full In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.
title_fullStr In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.
title_full_unstemmed In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.
title_short In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis.
title_sort in vitro clinical correlations for amphotericin b susceptibility in aids associated cryptococcal meningitis
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