Intramolecular cyclopropanation of unsaturated terminal epoxides.

Efficient lithium amide-induced intramolecular cyclopropanation of bishomoallylic and trishomoallylic epoxides is described. The methodology is used in an asymmetric synthesis of sabina ketone.

Podrobná bibliografie
Hlavní autoři: Hodgson, D, Chung, Y, Paris, J
Médium: Journal article
Jazyk:English
Vydáno: 2004
Popis
Shrnutí:Efficient lithium amide-induced intramolecular cyclopropanation of bishomoallylic and trishomoallylic epoxides is described. The methodology is used in an asymmetric synthesis of sabina ketone.