Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.

AIMS/HYPOTHESIS: We assessed whether per-arnt-sim (PAS) domain-containing protein kinase (PASK) is involved in the regulation of glucagon secretion. METHODS: mRNA levels were measured in islets by quantitative PCR and in pancreatic beta cells obtained by laser capture microdissection. Glucose tolera...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	da Silva Xavier, G, Farhan, H, Kim, H, Caxaria, S, Johnson, P, Hughes, S, Bugliani, M, Marselli, L, Marchetti, P, Birzele, F, Sun, G, Scharfmann, R, Rutter, J, Siniakowicz, K, Weir, G, Parker, H, Reimann, F, Gribble, F, Rutter, G
التنسيق:	Journal article
اللغة:	English
منشور في:	2011

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.

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