Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.

AIMS/HYPOTHESIS: We assessed whether per-arnt-sim (PAS) domain-containing protein kinase (PASK) is involved in the regulation of glucagon secretion. METHODS: mRNA levels were measured in islets by quantitative PCR and in pancreatic beta cells obtained by laser capture microdissection. Glucose tolera...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	da Silva Xavier, G, Farhan, H, Kim, H, Caxaria, S, Johnson, P, Hughes, S, Bugliani, M, Marselli, L, Marchetti, P, Birzele, F, Sun, G, Scharfmann, R, Rutter, J, Siniakowicz, K, Weir, G, Parker, H, Reimann, F, Gribble, F, Rutter, G
פורמט:	Journal article
שפה:	English
יצא לאור:	2011

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