Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.
AIMS/HYPOTHESIS: We assessed whether per-arnt-sim (PAS) domain-containing protein kinase (PASK) is involved in the regulation of glucagon secretion. METHODS: mRNA levels were measured in islets by quantitative PCR and in pancreatic beta cells obtained by laser capture microdissection. Glucose tolera...
Үндсэн зохиолчид: | da Silva Xavier, G, Farhan, H, Kim, H, Caxaria, S, Johnson, P, Hughes, S, Bugliani, M, Marselli, L, Marchetti, P, Birzele, F, Sun, G, Scharfmann, R, Rutter, J, Siniakowicz, K, Weir, G, Parker, H, Reimann, F, Gribble, F, Rutter, G |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2011
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