Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.

Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.

ABCB10 is one of the three ATP-binding cassette (ABC) transporters found in the inner membrane of mitochondria. In mammals ABCB10 is essential for erythropoiesis, and for protection of mitochondria against oxidative stress. ABCB10 is therefore a potential therapeutic target for diseases in which inc...

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Príomhchruthaitheoirí: Shintre, C, Pike, A, Li, Q, Kim, J, Barr, A, Goubin, S, Shrestha, L, Yang, J, Berridge, G, Ross, J, Stansfeld, P, Sansom, MS, Edwards, A, Bountra, C, Marsden, B, von Delft, F, Bullock, A, Gileadi, O, Burgess-Brown, N, Carpenter, E
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2013

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