CD8+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade.
BACKGROUND: The CD40-CD154 receptor-ligand pair plays a critical role in allograft rejection by mediating the activation of endothelial cells, antigen-presenting cells, and T cells. Blockade of this interaction prevents acute allograft rejection and leads to prolonged allograft survival in numerous...
Main Authors: | Ensminger, S, Witzke, O, Spriewald, B, Morrison, K, Morris, P, Rose, M, Wood, K |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2000
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פריטים דומים
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The persistence of transplant arteriosclerosis despite CD154 blockade.
מאת: Billing, J, et al.
יצא לאור: (2001) -
Intragraft interleukin-4 mRNA expression after short-term CD154 blockade may trigger delayed development of transplant arteriosclerosis in the absence of CD8+ T cells.
מאת: Ensminger, S, et al.
יצא לאור: (2000) -
Neutralizing interleukin-4 prevents transplant arteriosclerosis mediated by indirect pathway T cells under CD40-CD154 costimulation blockade.
מאת: Spriewald, B, et al.
יצא לאור: (2008) -
Critical role for IL-4 in the development of transplant arteriosclerosis in the absence of CD40-CD154 costimulation.
מאת: Ensminger, S, et al.
יצא לאור: (2001) -
Indirect allorecognition plays a pivotal role in the pathogenesis of transplant arteriosclerosis.
מאת: Ensminger, S, et al.
יצא לאור: (2000)