CD8+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade.

CD8+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade.

BACKGROUND: The CD40-CD154 receptor-ligand pair plays a critical role in allograft rejection by mediating the activation of endothelial cells, antigen-presenting cells, and T cells. Blockade of this interaction prevents acute allograft rejection and leads to prolonged allograft survival in numerous...

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Dettagli Bibliografici
Autori principali:	Ensminger, S, Witzke, O, Spriewald, B, Morrison, K, Morris, P, Rose, M, Wood, K
Natura:	Journal article
Lingua:	English
Pubblicazione:	2000

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