Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.

The lymphatic vasculature transports extravasated tissue fluid, macromolecules and cells back into the blood circulation. Recent reports have focused on the molecular mechanisms regulating the lymphatic vessels. Vascular endothelial growth factor (VEGF)-C and VEGF-D have been shown to stimulate lymp...

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Bibliographic Details
Main Authors: Mäkinen, T, Jussila, L, Veikkola, T, Karpanen, T, Kettunen, M, Pulkkanen, K, Kauppinen, R, Jackson, D, Kubo, H, Nishikawa, S, Ylä-Herttuala, S, Alitalo, K
Format: Journal article
Language:English
Published: 2001

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