Novel methodology for the detection of exercise-induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test.
BACKGROUND: We investigated whether ischemia-induced wall motion abnormalities during exercise test modify electrical vector variation. METHODS: We performed treadmill exercise test and thallium 201 scintigraphy in 150 normotensives. Beat-to-beat change of direction of S wave in V(1) (reference lea...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2011
|
| _version_ | 1797079947060183040 |
|---|---|
| author | Michaelides, A Massias, S Antoniades, C Tsiachris, D Dilaveris, P Aggelis, A Liakos, C Marinou, K Raftopoulos, L Soulis, D Stefanadis, C |
| author_facet | Michaelides, A Massias, S Antoniades, C Tsiachris, D Dilaveris, P Aggelis, A Liakos, C Marinou, K Raftopoulos, L Soulis, D Stefanadis, C |
| author_sort | Michaelides, A |
| collection | OXFORD |
| description | BACKGROUND: We investigated whether ischemia-induced wall motion abnormalities during exercise test modify electrical vector variation. METHODS: We performed treadmill exercise test and thallium 201 scintigraphy in 150 normotensives. Beat-to-beat change of direction of S wave in V(1) (reference lead) was compared with that of R wave in V(5) and aVF, representative of anterior and inferior walls, respectively. The percentage of neighboring QRS couples where S wave in V(1) and R wave in V(5) or aVF change toward the same direction (increase or decrease) constitutes V1-V5 and V1-aVF indexes. RESULTS: V1-V5 and V1-aVF indexes were significantly decreased in subjects with reversible anterior or inferior ischemia, respectively. A decrease in V1-V5 index ≥0.14 defines those with anterior wall ischemia (sensitivity, 100%; specificity, 75.5%), whereas a decrease in V1-aVF index ≥0.05 defines those with inferior wall ischemia (sensitivity, 92.3%; specificity, 61.5%). CONCLUSIONS: These novel electrocardiographic exercise test indexes improved significantly their sensitivities. |
| first_indexed | 2024-03-07T00:53:09Z |
| format | Journal article |
| id | oxford-uuid:87174f9d-d392-43e5-a9a6-db47d183781c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:53:09Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:87174f9d-d392-43e5-a9a6-db47d183781c2022-03-26T22:08:28ZNovel methodology for the detection of exercise-induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:87174f9d-d392-43e5-a9a6-db47d183781cEnglishSymplectic Elements at Oxford2011Michaelides, AMassias, SAntoniades, CTsiachris, DDilaveris, PAggelis, ALiakos, CMarinou, KRaftopoulos, LSoulis, DStefanadis, C BACKGROUND: We investigated whether ischemia-induced wall motion abnormalities during exercise test modify electrical vector variation. METHODS: We performed treadmill exercise test and thallium 201 scintigraphy in 150 normotensives. Beat-to-beat change of direction of S wave in V(1) (reference lead) was compared with that of R wave in V(5) and aVF, representative of anterior and inferior walls, respectively. The percentage of neighboring QRS couples where S wave in V(1) and R wave in V(5) or aVF change toward the same direction (increase or decrease) constitutes V1-V5 and V1-aVF indexes. RESULTS: V1-V5 and V1-aVF indexes were significantly decreased in subjects with reversible anterior or inferior ischemia, respectively. A decrease in V1-V5 index ≥0.14 defines those with anterior wall ischemia (sensitivity, 100%; specificity, 75.5%), whereas a decrease in V1-aVF index ≥0.05 defines those with inferior wall ischemia (sensitivity, 92.3%; specificity, 61.5%). CONCLUSIONS: These novel electrocardiographic exercise test indexes improved significantly their sensitivities. |
| spellingShingle | Michaelides, A Massias, S Antoniades, C Tsiachris, D Dilaveris, P Aggelis, A Liakos, C Marinou, K Raftopoulos, L Soulis, D Stefanadis, C Novel methodology for the detection of exercise-induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test. |
| title | Novel methodology for the detection of exercise-induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test. |
| title_full | Novel methodology for the detection of exercise-induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test. |
| title_fullStr | Novel methodology for the detection of exercise-induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test. |
| title_full_unstemmed | Novel methodology for the detection of exercise-induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test. |
| title_short | Novel methodology for the detection of exercise-induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test. |
| title_sort | novel methodology for the detection of exercise induced myocardial wall motion abnormalities by surface electrocardiogram during exercise test |
| work_keys_str_mv | AT michaelidesa novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT massiass novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT antoniadesc novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT tsiachrisd novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT dilaverisp novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT aggelisa novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT liakosc novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT marinouk novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT raftopoulosl novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT soulisd novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest AT stefanadisc novelmethodologyforthedetectionofexerciseinducedmyocardialwallmotionabnormalitiesbysurfaceelectrocardiogramduringexercisetest |