New methods for the construction of C-18F bonds
<p>The main electrophilic source used in radiolabelling is [18F]F2, which is highly reactive, toxic and requires specialist equipment for safe handling. The Gouverneur group has initiated a research programme focused on the preparation of new stable and easy-to-handle N-18F reagents. In the de...
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| Formáid: | Tráchtas |
| Teanga: | English |
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2014
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| _version_ | 1826311950396555264 |
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| author | Stenhagen, I |
| author2 | Gouverneur, V |
| author_facet | Gouverneur, V Stenhagen, I |
| author_sort | Stenhagen, I |
| collection | OXFORD |
| description | <p>The main electrophilic source used in radiolabelling is [18F]F2, which is highly reactive, toxic and requires specialist equipment for safe handling. The Gouverneur group has initiated a research programme focused on the preparation of new stable and easy-to-handle N-18F reagents. In the development of [18F]radiolabelling reactions it would be extremely valuable to develop a library of selective N-18F reagents possessing reactivity tailored to the desired chemical transformation. The aim of this thesis is to further assess the scope of electrophilic N- 18F reagents in new transformations for the construction of C-18F bonds.</p> |
| first_indexed | 2024-03-07T08:18:51Z |
| format | Thesis |
| id | oxford-uuid:871a7e8c-a4d3-4acb-a25d-5946dec2f44d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T08:18:51Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | oxford-uuid:871a7e8c-a4d3-4acb-a25d-5946dec2f44d2024-01-16T16:04:02ZNew methods for the construction of C-18F bondsThesishttp://purl.org/coar/resource_type/c_db06uuid:871a7e8c-a4d3-4acb-a25d-5946dec2f44dOrganic synthesisOrganometallic ChemistryOrganic chemistryEnglishOxford University Research Archive - Valet2014Stenhagen, IGouverneur, V<p>The main electrophilic source used in radiolabelling is [18F]F2, which is highly reactive, toxic and requires specialist equipment for safe handling. The Gouverneur group has initiated a research programme focused on the preparation of new stable and easy-to-handle N-18F reagents. In the development of [18F]radiolabelling reactions it would be extremely valuable to develop a library of selective N-18F reagents possessing reactivity tailored to the desired chemical transformation. The aim of this thesis is to further assess the scope of electrophilic N- 18F reagents in new transformations for the construction of C-18F bonds.</p> |
| spellingShingle | Organic synthesis Organometallic Chemistry Organic chemistry Stenhagen, I New methods for the construction of C-18F bonds |
| title | New methods for the construction of C-18F bonds |
| title_full | New methods for the construction of C-18F bonds |
| title_fullStr | New methods for the construction of C-18F bonds |
| title_full_unstemmed | New methods for the construction of C-18F bonds |
| title_short | New methods for the construction of C-18F bonds |
| title_sort | new methods for the construction of c 18f bonds |
| topic | Organic synthesis Organometallic Chemistry Organic chemistry |
| work_keys_str_mv | AT stenhageni newmethodsfortheconstructionofc18fbonds |