Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2

Despite high-hyperdiploid acute lymphoblastic leukaemia (HD-ALL) being the most common subgroup of paediatric ALL, its aetiology remains unknown. Genome-wide association studies have demonstrated association at 10q21.2. Here, we sought to determine how this region influences HD-ALL risk. We impute g...

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Bibliographic Details
Main Authors: Studd, J, Vijayakrishnan, J, Yang, M, Migliorini, G, Paulsson, K, Houlston, R
Format: Journal article
Language:English
Published: Springer Nature 2017