Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1-13C]pyruvate
Purpose: To demonstrate the feasibility of mapping intracellular pH within the in vivo rodent heart. Introduction: Alterations in cardiac acid-base balance can lead to acute contractile depression and alterations in Ca2+ signalling. The transient reduction in ATP consumption and cardiac contractili...
المؤلفون الرئيسيون: | Lau, A, Miller, J, Tyler, D |
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مؤلفون آخرون: | Ernst, T |
التنسيق: | Journal article |
منشور في: |
Wiley
2016
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مواد مشابهة
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Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-(13)C2]pyruvate in vivo.
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In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance.
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Rapid multislice imaging of hyperpolarized 13C pyruvate and bicarbonate in the heart.
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Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2- C ]pyruvate in vivo
حسب: Chen, A, وآخرون
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Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart.
حسب: Schroeder, M, وآخرون
منشور في: (2013)