Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1-13C]pyruvate

Purpose: To demonstrate the feasibility of mapping intracellular pH within the in vivo rodent heart. Introduction: Alterations in cardiac acid-base balance can lead to acute contractile depression and alterations in Ca2+ signalling. The transient reduction in ATP consumption and cardiac contractili...

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Príomhchruthaitheoirí: Lau, A, Miller, J, Tyler, D
Rannpháirtithe: Ernst, T
Formáid: Journal article
Foilsithe / Cruthaithe: Wiley 2016