The impact of an extended nucleobase-2′-deoxyribose linker in the biophysical and biological properties of oligonucleotides

Interest in artificial DNA mimetics has been triggered by the widespread applications of nucleic acids as they are useful tools for modulation of the biophysical and biological properties of oligonucleotides. In this article, we describe the synthesis and properties of a novel thymine derivative (T*...

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Bibliografiske detaljer
Main Authors: Carnero, A, Pérez-Rentero, S, Alagia, A, Aviñó, A, Sanghvi, Y, Fernández, S, Ferrero, M, Eritja, R
Format: Journal article
Udgivet: Royal Society of Chemistry 2017