An HIV-1 and HIV-2 cross-reactive cytotoxic T-cell epitope.

An HIV-1 and HIV-2 cross-reactive cytotoxic T-cell epitope.

The HLA-B27-restricted HIV gag cytotoxic T-lymphocyte (CTL) epitope, 265-279, is highly conserved amongst HIV-1 isolates, only one, HIV-1ELI, having a single amino acid substitution. Over the same region HIV-2 differs by five amino acids. As a broadly cross-protective AIDS vaccine should protect aga...

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Bibliographic Details
Main Authors:	Nixon, D, Huet, S, Rothbard, J, Kieny, M, Delchambre, M, Thiriart, C, Rizza, C, Gotch, F, Mcmichael, A
Format:	Journal article
Language:	English
Published:	1990

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