A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt

A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt

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The surface epithelium lining the intestinal tract renews itself rapidly by a coordinated programme of cell proliferation, migration and differentiation events that is initiated in the crypts of Lieberkuhn. It is generally believed that colorectal cancer arises due to mutations that disrupt the norm...

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Autors principals:	Mirams, G, Fletcher, A, Maini, P, Byrne, H
Format:	Journal article
Publicat:	2012

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