Direct measurements of relaxation times of phosphorus metabolites in the human myocardium
The T1 relaxation times of the phosphorus metabolites in human heart muscle measurable by 31P-MR spectra were determined in 12 individuals using a 1.5 Tesla system. Several spectra were recorded consecutively with a pulse repetition time of 1.6 s to 24 s. The T1 times of creatine phosphate (CP), of...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | German |
| Published: |
1992
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| _version_ | 1826283167460360192 |
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| author | Schindler, R Krahe, T Neubauer, S Hillenbrand, H Entzeroth, C Horn, M Lackner, K Ertl, G |
| author_facet | Schindler, R Krahe, T Neubauer, S Hillenbrand, H Entzeroth, C Horn, M Lackner, K Ertl, G |
| author_sort | Schindler, R |
| collection | OXFORD |
| description | The T1 relaxation times of the phosphorus metabolites in human heart muscle measurable by 31P-MR spectra were determined in 12 individuals using a 1.5 Tesla system. Several spectra were recorded consecutively with a pulse repetition time of 1.6 s to 24 s. The T1 times of creatine phosphate (CP), of γ-, α-, β-adenosintriphosphate (ATP), 2,3-diphosphoglycerate (2,3-DPG) together with anorganic phosphate) and phosphodiester (PDE) showed mean measurements of 6.1 ± 0.5, 5.4 ± 0.5, 5.0 ± 0.5, 5.8 ± 1.0, 7.6 ± 1.0, and 5.0 ± 1.0 s (M ± SE). The accuracy of the ISIS technique was tested with a special phantom. T1 times were also measured in standard solutions (20mM CP, 10mM ATP); CP was 8.7 ± 0.2 s and γ-ATP was 9.9 ± 0.7 s. Corrections for partially saturated 31P-MR spectra - at least for CP/ATP ratios - are relatively small. |
| first_indexed | 2024-03-07T00:54:50Z |
| format | Journal article |
| id | oxford-uuid:87b12041-337e-486d-b5a1-96c1aeaa8c6f |
| institution | University of Oxford |
| language | German |
| last_indexed | 2024-03-07T00:54:50Z |
| publishDate | 1992 |
| record_format | dspace |
| spelling | oxford-uuid:87b12041-337e-486d-b5a1-96c1aeaa8c6f2022-03-26T22:12:16ZDirect measurements of relaxation times of phosphorus metabolites in the human myocardiumJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:87b12041-337e-486d-b5a1-96c1aeaa8c6fGermanSymplectic Elements at Oxford1992Schindler, RKrahe, TNeubauer, SHillenbrand, HEntzeroth, CHorn, MLackner, KErtl, GThe T1 relaxation times of the phosphorus metabolites in human heart muscle measurable by 31P-MR spectra were determined in 12 individuals using a 1.5 Tesla system. Several spectra were recorded consecutively with a pulse repetition time of 1.6 s to 24 s. The T1 times of creatine phosphate (CP), of γ-, α-, β-adenosintriphosphate (ATP), 2,3-diphosphoglycerate (2,3-DPG) together with anorganic phosphate) and phosphodiester (PDE) showed mean measurements of 6.1 ± 0.5, 5.4 ± 0.5, 5.0 ± 0.5, 5.8 ± 1.0, 7.6 ± 1.0, and 5.0 ± 1.0 s (M ± SE). The accuracy of the ISIS technique was tested with a special phantom. T1 times were also measured in standard solutions (20mM CP, 10mM ATP); CP was 8.7 ± 0.2 s and γ-ATP was 9.9 ± 0.7 s. Corrections for partially saturated 31P-MR spectra - at least for CP/ATP ratios - are relatively small. |
| spellingShingle | Schindler, R Krahe, T Neubauer, S Hillenbrand, H Entzeroth, C Horn, M Lackner, K Ertl, G Direct measurements of relaxation times of phosphorus metabolites in the human myocardium |
| title | Direct measurements of relaxation times of phosphorus metabolites in the human myocardium |
| title_full | Direct measurements of relaxation times of phosphorus metabolites in the human myocardium |
| title_fullStr | Direct measurements of relaxation times of phosphorus metabolites in the human myocardium |
| title_full_unstemmed | Direct measurements of relaxation times of phosphorus metabolites in the human myocardium |
| title_short | Direct measurements of relaxation times of phosphorus metabolites in the human myocardium |
| title_sort | direct measurements of relaxation times of phosphorus metabolites in the human myocardium |
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