Cancer in patients receiving dialysis.
The incidence of cancer and related mortality was studied in 1651 patients from six dialysis centres in England over 10 years. The only type of cancer for which there was a significant excess was non-Hodgkin's lymphoma (four cases observed against an expected incidence of 0.15 (p < 0.001...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1980
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| _version_ | 1797080081434148864 |
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| author | Kinlen, L Eastwood, J Kerr, D Moorhead, J Oliver, DO Robinson, B de Wardener, H Wing, A |
| author_facet | Kinlen, L Eastwood, J Kerr, D Moorhead, J Oliver, DO Robinson, B de Wardener, H Wing, A |
| author_sort | Kinlen, L |
| collection | OXFORD |
| description | The incidence of cancer and related mortality was studied in 1651 patients from six dialysis centres in England over 10 years. The only type of cancer for which there was a significant excess was non-Hodgkin's lymphoma (four cases observed against an expected incidence of 0.15 (p < 0.001); three deaths against an expected 0.1 (p < 0.001)). This excess could not be attributed to either subsequent transplantation or treatment with immunosuppressive drugs. Since immunodepression is a feature of chronic renal failure, these observations together with those on patints treated with immunosuppressive drugs suggest that immunosuppression favours the development of non-Hodgkin's lymphoma. Studies in which it is concluded that patients receiving dialysis show an excess of other types of cancer have certain shortcomings; the unusual opportunities for detecting cancer in such patients may account for some of the reported excess. |
| first_indexed | 2024-03-07T00:55:03Z |
| format | Journal article |
| id | oxford-uuid:87c3905c-a0fb-46dc-b0dd-d4049f2ed78d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:55:03Z |
| publishDate | 1980 |
| record_format | dspace |
| spelling | oxford-uuid:87c3905c-a0fb-46dc-b0dd-d4049f2ed78d2022-03-26T22:12:43ZCancer in patients receiving dialysis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:87c3905c-a0fb-46dc-b0dd-d4049f2ed78dEnglishSymplectic Elements at Oxford1980Kinlen, LEastwood, JKerr, DMoorhead, JOliver, DORobinson, Bde Wardener, HWing, AThe incidence of cancer and related mortality was studied in 1651 patients from six dialysis centres in England over 10 years. The only type of cancer for which there was a significant excess was non-Hodgkin's lymphoma (four cases observed against an expected incidence of 0.15 (p < 0.001); three deaths against an expected 0.1 (p < 0.001)). This excess could not be attributed to either subsequent transplantation or treatment with immunosuppressive drugs. Since immunodepression is a feature of chronic renal failure, these observations together with those on patints treated with immunosuppressive drugs suggest that immunosuppression favours the development of non-Hodgkin's lymphoma. Studies in which it is concluded that patients receiving dialysis show an excess of other types of cancer have certain shortcomings; the unusual opportunities for detecting cancer in such patients may account for some of the reported excess. |
| spellingShingle | Kinlen, L Eastwood, J Kerr, D Moorhead, J Oliver, DO Robinson, B de Wardener, H Wing, A Cancer in patients receiving dialysis. |
| title | Cancer in patients receiving dialysis. |
| title_full | Cancer in patients receiving dialysis. |
| title_fullStr | Cancer in patients receiving dialysis. |
| title_full_unstemmed | Cancer in patients receiving dialysis. |
| title_short | Cancer in patients receiving dialysis. |
| title_sort | cancer in patients receiving dialysis |
| work_keys_str_mv | AT kinlenl cancerinpatientsreceivingdialysis AT eastwoodj cancerinpatientsreceivingdialysis AT kerrd cancerinpatientsreceivingdialysis AT moorheadj cancerinpatientsreceivingdialysis AT oliverdo cancerinpatientsreceivingdialysis AT robinsonb cancerinpatientsreceivingdialysis AT dewardenerh cancerinpatientsreceivingdialysis AT winga cancerinpatientsreceivingdialysis |