Hypothyroidism in utero stimulates pancreatic beta cell proliferation and hyperinsulinaemia in the ovine fetus during late gestation
Development of pancreatic beta cell mass before birth is essential for normal growth of the fetus and for long-term control of carbohydrate metabolism in postnatal life. Thyroid hormones are also important regulators of fetal growth, and the present study tested the hypotheses that thyroid hormones...
Main Authors: | Harris, S, De Blasio, M, Davis, M, Kelly, A, Davenport, H, Wooding, F, Blache, D, Meredith, D, Anderson, M, Fowden, A, Limesand, S, Forhead, A |
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Format: | Journal article |
Published: |
Wiley
2017
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