Progressive epidural lipomatosis with steroid use in severe refractory asthma.
BACKGROUND: Long-term immunosuppression with oral corticosteroids is frequently used to treat inflammatory diseases of the lung and is advocated in the management of some patients with asthma. METHODS: The authors describe the case of a 35-year-old man with severe refractory asthma who developed a...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2011
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| _version_ | 1797080087984603136 |
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| author | Wakerley, B Kent, L Jackson, M |
| author_facet | Wakerley, B Kent, L Jackson, M |
| author_sort | Wakerley, B |
| collection | OXFORD |
| description | BACKGROUND: Long-term immunosuppression with oral corticosteroids is frequently used to treat inflammatory diseases of the lung and is advocated in the management of some patients with asthma. METHODS: The authors describe the case of a 35-year-old man with severe refractory asthma who developed a slowly progressive thoracic spinal cord syndrome. RESULTS: Spinal imaging demonstrated the presence of spinal epidural lipomatosis, a rare complication of prolonged corticosteroid therapy, which is characterized by overgrowth of fat in the epidural space and neuronal compression. CONCLUSIONS: Spinal epidural lipomatosis should be considered in patients receiving long-term corticosteroid therapy who develop symptoms and signs suggestive of spinal cord compression. |
| first_indexed | 2024-03-07T00:55:09Z |
| format | Journal article |
| id | oxford-uuid:87cc6eea-ec29-404a-b7fd-fcdb6062406f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:55:09Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:87cc6eea-ec29-404a-b7fd-fcdb6062406f2022-03-26T22:12:56ZProgressive epidural lipomatosis with steroid use in severe refractory asthma.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:87cc6eea-ec29-404a-b7fd-fcdb6062406fEnglishSymplectic Elements at Oxford2011Wakerley, BKent, LJackson, M BACKGROUND: Long-term immunosuppression with oral corticosteroids is frequently used to treat inflammatory diseases of the lung and is advocated in the management of some patients with asthma. METHODS: The authors describe the case of a 35-year-old man with severe refractory asthma who developed a slowly progressive thoracic spinal cord syndrome. RESULTS: Spinal imaging demonstrated the presence of spinal epidural lipomatosis, a rare complication of prolonged corticosteroid therapy, which is characterized by overgrowth of fat in the epidural space and neuronal compression. CONCLUSIONS: Spinal epidural lipomatosis should be considered in patients receiving long-term corticosteroid therapy who develop symptoms and signs suggestive of spinal cord compression. |
| spellingShingle | Wakerley, B Kent, L Jackson, M Progressive epidural lipomatosis with steroid use in severe refractory asthma. |
| title | Progressive epidural lipomatosis with steroid use in severe refractory asthma. |
| title_full | Progressive epidural lipomatosis with steroid use in severe refractory asthma. |
| title_fullStr | Progressive epidural lipomatosis with steroid use in severe refractory asthma. |
| title_full_unstemmed | Progressive epidural lipomatosis with steroid use in severe refractory asthma. |
| title_short | Progressive epidural lipomatosis with steroid use in severe refractory asthma. |
| title_sort | progressive epidural lipomatosis with steroid use in severe refractory asthma |
| work_keys_str_mv | AT wakerleyb progressiveepidurallipomatosiswithsteroiduseinsevererefractoryasthma AT kentl progressiveepidurallipomatosiswithsteroiduseinsevererefractoryasthma AT jacksonm progressiveepidurallipomatosiswithsteroiduseinsevererefractoryasthma |