Exhaustive differentiation of alloreactive CD8+ T cells: critical for determination of graft acceptance or rejection.
BACKGROUND: The precise role that CD8+ T cells play in the rejection and acceptance of different types of allograft is unclear and has been shown to vary between donor-recipient combinations. METHODS: The response of adoptively transferred CD8+ T cells reactive to the donor alloantigen H2Kb was exa...
मुख्य लेखकों: | Steger, U, Denecke, C, Sawitzki, B, Karim, M, Jones, N, Wood, K |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2008
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समान संसाधन
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CD25+CD4+ regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection.
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Identification of gene markers for the prediction of allograft rejection or permanent acceptance.
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Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection.
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Delayed anti-CD3 therapy results in depletion of alloreactive T cells and the dominance of Foxp3+ CD4+ graft infiltrating cells.
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प्रकाशित: (2013)