STEPWISE HYDROGEN REMOVAL IN THE ENZYMATIC RING EXPANSION OF PENICILLIN-N TO DEACETOXYCEPHALOSPORIN-C

STEPWISE HYDROGEN REMOVAL IN THE ENZYMATIC RING EXPANSION OF PENICILLIN-N TO DEACETOXYCEPHALOSPORIN-C

Reaction of a 1:1 mixture of penicillin N and 2,2-bis(trideuteriomethyl) penicillin N with partially purified deacetoxy-cephalosporin C/deacetylcephalosporin C synthetase from Cephalosporium acremonium CO 728 resulted in preferential conversion of the protiated substrate, whereas in similar experime...

Detaylı Bibliyografya
Asıl Yazarlar:	Baldwin, J, Adlington, R, Aplin, R, Crouch, N, Schofield, C, Ting, H
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	1987

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