STEPWISE HYDROGEN REMOVAL IN THE ENZYMATIC RING EXPANSION OF PENICILLIN-N TO DEACETOXYCEPHALOSPORIN-C

Reaction of a 1:1 mixture of penicillin N and 2,2-bis(trideuteriomethyl) penicillin N with partially purified deacetoxy-cephalosporin C/deacetylcephalosporin C synthetase from Cephalosporium acremonium CO 728 resulted in preferential conversion of the protiated substrate, whereas in similar experime...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Baldwin, J, Adlington, R, Aplin, R, Crouch, N, Schofield, C, Ting, H
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1987