STEPWISE HYDROGEN REMOVAL IN THE ENZYMATIC RING EXPANSION OF PENICILLIN-N TO DEACETOXYCEPHALOSPORIN-C
Reaction of a 1:1 mixture of penicillin N and 2,2-bis(trideuteriomethyl) penicillin N with partially purified deacetoxy-cephalosporin C/deacetylcephalosporin C synthetase from Cephalosporium acremonium CO 728 resulted in preferential conversion of the protiated substrate, whereas in similar experime...
Những tác giả chính: | , , , , , |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
1987
|