Towards a Grid infrastructure to support integrative approaches to biological research
This paper discusses the scientific rationale behind the e-Science project, Integrative Biology, which is developing mathematical modelling tools, HPC-enabled simulations and an underpinning Grid infrastructure to provide an integrative approach to the modelling of complex biological systems. The pr...
| Päätekijät: | , , , , |
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| Aineistotyyppi: | Journal article |
| Julkaistu: |
2005
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| _version_ | 1826283280599613440 |
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| author | Gavaghan, D Simpson, A Lloyd, S Mac, R Boyd, D |
| author_facet | Gavaghan, D Simpson, A Lloyd, S Mac, R Boyd, D |
| author_sort | Gavaghan, D |
| collection | OXFORD |
| description | This paper discusses the scientific rationale behind the e-Science project, Integrative Biology, which is developing mathematical modelling tools, HPC-enabled simulations and an underpinning Grid infrastructure to provide an integrative approach to the modelling of complex biological systems. The project is focusing on two key applications to validate the approach: the modelling of heart disease and cancer, which together are responsible for over 60% of deaths in the United Kingdom. This paper provides an overview of the project, describes the initial prototype architecture and discusses the long-term scientific aims |
| first_indexed | 2024-03-07T00:56:33Z |
| format | Journal article |
| id | oxford-uuid:88455e59-7494-498e-b20f-33c0f3c7fe01 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T00:56:33Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:88455e59-7494-498e-b20f-33c0f3c7fe012022-03-26T22:16:07ZTowards a Grid infrastructure to support integrative approaches to biological researchJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:88455e59-7494-498e-b20f-33c0f3c7fe01Department of Computer Science2005Gavaghan, DSimpson, ALloyd, SMac, RBoyd, DThis paper discusses the scientific rationale behind the e-Science project, Integrative Biology, which is developing mathematical modelling tools, HPC-enabled simulations and an underpinning Grid infrastructure to provide an integrative approach to the modelling of complex biological systems. The project is focusing on two key applications to validate the approach: the modelling of heart disease and cancer, which together are responsible for over 60% of deaths in the United Kingdom. This paper provides an overview of the project, describes the initial prototype architecture and discusses the long-term scientific aims |
| spellingShingle | Gavaghan, D Simpson, A Lloyd, S Mac, R Boyd, D Towards a Grid infrastructure to support integrative approaches to biological research |
| title | Towards a Grid infrastructure to support integrative approaches to biological research |
| title_full | Towards a Grid infrastructure to support integrative approaches to biological research |
| title_fullStr | Towards a Grid infrastructure to support integrative approaches to biological research |
| title_full_unstemmed | Towards a Grid infrastructure to support integrative approaches to biological research |
| title_short | Towards a Grid infrastructure to support integrative approaches to biological research |
| title_sort | towards a grid infrastructure to support integrative approaches to biological research |
| work_keys_str_mv | AT gavaghand towardsagridinfrastructuretosupportintegrativeapproachestobiologicalresearch AT simpsona towardsagridinfrastructuretosupportintegrativeapproachestobiologicalresearch AT lloyds towardsagridinfrastructuretosupportintegrativeapproachestobiologicalresearch AT macr towardsagridinfrastructuretosupportintegrativeapproachestobiologicalresearch AT boydd towardsagridinfrastructuretosupportintegrativeapproachestobiologicalresearch |