RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells

Development and function of pancreatic β cells involve the regulated activity of specific transcription factors. RFX6 is a transcription factor essential for mouse β cell differentiation that is mutated in monogenic forms of neonatal diabetes. However, the expression and functional roles of RFX6 in...

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Main Authors: Chandra, V, Albagli-Curiel, O, Hastoy, B, Piccand, J, Randriamampita, C, Vaillant, E, Cavé, H, Busiah, K, Froguel, P, Vaxillaire, M, Rorsman, P, Polak, M, Scharfmann, R
格式: Journal article
语言:English
出版: Elsevier 2014