Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours.

OBJECTIVES: Somatostatin (SST) analogues play an important role in the medical management of somatotroph pituitary adenomas and new agonists have the potential to be effective in a wider group of pituitary and other tumours. The anti-proliferative effect of SST occurs through multiple mechanisms, o...

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Bibliographic Details
Main Authors: Hubina, E, Nanzer, A, Hanson, MR, Ciccarelli, E, Losa, M, Gaia, D, Papotti, M, Terreni, MR, Khalaf, S, Jordan, S, Czirják, S, Hanzély, Z, Nagy, G, Góth, M, Grossman, AB, Korbonits, M
Format: Journal article
Language:English
Published: 2006